Part I Introduction to astrobiology.- 1. What is astrobiology.- Part II Physics and chemistry from space to life.- 2. Theory of universe and life.- 3. Complex organic molecules in Space.- 4. Chemical relationships among organics, water and minerals in the early Solar System.- 5. Prebiotic synthesis of bioorganic compounds by simulation experiments.- 6. RNA synthesis before the origin of life.- Part III History of life reveiled from bilology.- 7. RNA world.- 8. Common ancestor.- 9. Eukaryotes appearing.- 10. Collor of photosynthetic system.- 11. Evolution of photosynthetic system.- 12. History and evolution of intelligence on the Earth.- Part IV History of the Earth reveiled from geology.- 13. Origin of planets.- 14. Evolution of early atmosphere.- 15. Biogenic graphite in ancient rocks.- 16. Fossilized early cells and their implications for biotic diversity in the Archean.- 17. Great oxidation event.- 18. Mass extinction P-Tr.- 19. Mass extinction at K-Pg boundary.- Part V. Search for life in solar system and extra solar system.- 20. Limits of terrestrial life and biosphere.- 21. Mars we know of.- 22. Atmosphere of Mars.- 23. Life search on Mars.- 24. Active surface and interior of Europa as a potential deep habitat.- 25. Enceladus.- 26. Titan.- 27. Panspermia hypothesis.- 28. Extra-solar planetary systems.- 29. Life in a second earth.- 30. Search for extra-terrestrial intelligence.- 31. Possible impact if extraterrestrial life, if it were to be found.